The most common neurological issue in Costello syndrome is hypotonia, or low muscle tone.This means that the person with CS shows little resistance when the limbs are moved. Tone is different from strength, and CS…

Because there can be number of different brain issues, and it is helpful to compare early imaging studies to later studies, it may be a good idea to have a brain and upper spinal cord…

If an EEG was done, sometimes a second study several months or years after the first study is needed. We are still learning about Costello syndrome, and about how it affects the brain and spinal…